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The inducible HMOX isoform (HMOX1, OMIM*141250), a member of the heat-shock protein HSP32 family, is activated by a number of oxidative stress-provoking stimuli

Another pathway of interest is the serine biosynthesis axis, centered on the phosphoglycerate dehydrogenase (PHGDH), which diverts glycolytic intermediates to produce serine [144]

The overall performance of both algorithms when using MASEF score or LSM by VCTE as the second test after FIB-4 did not show significant differences (p=0.69)

We further elucidate how aging, environmental toxicants, lifestyle choices, and pathological conditions such as cystic ovaries and endometriosis exacerbate oxidative damage, thereby severely compromising meiotic competence and embryonic development