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Moreover, the imbalance in microbiota composition skews immune cell differentiation toward pro-inflammatory phenotypes, particularly Th 1 and Th 17 cells, and concurrently diminishes the function and numbers of regulatory T cells, thereby enhancing the risk and severity of autoimmune thyroid diseases (Takiishi et al., 2017)

the original research studies instead used intravenous or intracerebroventricular administration, which is a meaningfully different route and context

V., Ryzhak, G

LF-to-HF ratio was not associated with hypertension, but all other HRV parameters had a negative association with older age and hypertension