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(1986) investigated the pharmacokinetics of ergotamine (2 mg) in healthy volunteers ( n = 24) after oral and rectal dosing

Each treatment was compared to the vehicle (DMF) control treatment in either mock or GSTP1 cells

Aerobic-based training was performed on a motorized treadmill, and intensities were determined by age-predicted heart rate max (HR max = 220 beats per minute-age) and Rate of Perceived Exertion (RPE) using Borgs original scale (620 points)