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Description

Hinokitiol functions as a ferroptosis inhibitor to confer neuroprotection

It was shown that gating is produced due to persulfidation of a cysteine close to the narrow channel after treatment with H 2 S/HS , probably preceded by a transient sulfenic acid intermediate ( Many cases have been reported in which the persulfidation of cysteines in active sites of enzymes disrupted atomic distances and hydrogen bonding tailored for catalysis