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doi: 10.1128/MCB.00256-15 Summary Keywords bacterial infections, cell signaling, phospholipase C, tuberculosis, phospholipids (PL), Listeria monocytogenes , Helicobabacter pylori , Clostridium perfringens Citation Singh V, Rai R, Mathew BJ, Chourasia R, Singh AK, Kumar A and Chaurasiya SK (2023) Phospholipase C: underrated players in microbial infections

Moreover, EMT can enhance the secretion of TGF- and inflammatory cytokines by damaged epithelial cells, which, respectively, promote the differentiation of fibroblasts into myofibroblasts and trigger immune inflammation, ultimately resulting in repair failure and tissue fibrosis (83, 84)

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Conversely, other metabolic products may serve as strong enzyme inhibitors