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The cumulative transdermal rate (%) was calculated as: where Vi is the volume of the i -th sample aliquot, Ci is the mass concentration of the API in the i -th sample, V is the total volume of the receptor compartment solution, Cn is the API concentration in the n -th sample, and Cm and Vm are the initial API concentration and volume of the medium, respectively

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Other drugs may affect semaglutide, including prescription and over-the-counter medicines, vitamins, and herbal products

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