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Additionally, exposure to ROS can lead to modifications that cause genomic DNA mutations, negatively affect protein activity, damage cellular membranes, and eventually leading to cell death

In this review, we synthesize recent advances in our understanding of gutbrain communication with a focus on prevention and intervention strategies

CMA defects are also observed in AD

Without enough glutathione, mercury can damage the brain and also take the place of selenium in certain biological pathways.[ref] Related article : Mercury, detoxification, and your genes Alcohol: Acute or chronic alcohol exposure leads to a depletion of glutathione in the liver and liver damage