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Wijarnpreecha K, Werlang M, Panjawatanan P, Pungpapong S, Lukens FJ, Harnois DM, et al

The KRAS protein is a small GTP hydrolysis enzyme (small GTPase) that frequently undergoes mutation in NSCLC

When MAPK/ERK1/2 and p38 MAPK signaling pathways begin, the result is the common denominator of signaling pathways, which alter gene expression, metabolism, and cell proliferation [43]