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The density of dendritic spines is closely associated with memory enhancement and 23 was found to increase the density of spines in the hippocampus significantly

FDA's evaluation concluded that the criteria weighed against placement on the list, citing inadequate physicochemical characterization, immunogenicity concerns from impurities and aggregates, lack of clinical effectiveness data for any approved use, and absence of published human exposure data for the proposed subcutaneous and topical routes

Research suggests that it may be associated with cytoprotective mechanisms and tissue repair processes in preclinical musculoskeletal, gastrointestinal, neurologic, and vascular injury models

PLoS ONE 12:e0171524 Morn JA, Brockington A, Wise RA et al (2002) Dopamine uptake through the norepinephrine transporter in brain regions with low levels of the dopamine transporter: evidence from knock-out mouse lines