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In addition, excessive formaldehyde can impair cognitive functions by inhibiting N-methyl-D-aspartate (NMDA) receptors and exacerbating brain IR

Instead, the hyperfunctioning nodule inappropriately secretes excess thyroid hormone which leads to hyperthyroidism

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It participates in one-carbon metabolism and is converted to oxaloacetate or formic acid through the glycine cleavage system (GCS), while simultaneously releasing ammonia and carbon dioxide