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The neurodegeneration is associated with decontrolled inflammatory responses into the CNS

Recently, the MiOXSYS system has be proposed as a standardized assessment of seminal oxidative stress due to its ease of use, cost effectiveness, and reproducibility, as well as proposed evidence based clinical guidelines [150, 151]

Such aspects, and much more including glutathione-boosting substances administrable to humans, are considered in this state-of-the-art review, which deals with glutathione and glutathione-dependent enzymes from biochemistry to gerontology, focusing attention also on lifespan/healthspan extension and successful aging