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doi: 10.3390/cells11162472 238 MaZChenWLiuYYuLMaoXGuoXet al

Angeli, L

K.AlmoshariY.WangH.WangX.ReinhardtR

Further research is needed to elucidate the basic mechanism underpinning T and B-cell recruitment into an immune response, to examine antibody affinity maturation and to identify the determinants of the immunodominance hierarchy for T and B-cell epitopes, which ultimately may enable vaccine antigens to be rationally designed to induce broadly targeted immunity