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In contrast, CK-stress treatment strongly suppressed most phenolic compounds, suggesting downregulation of the phenylpropanoid pathway and insufficient oxidative stress mitigation

Hepcidin, a major iron regulatory and endogenous ferroptosis protective molecule, has been shown to decrease the availability of free iron, reduce macrophage and T cell infiltration in the kidneys, and further improve renal inflammation, thus alleviating the severity of lupus nephritis in susceptible mouse models

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Evidence that TDP-43 is not the major ubiquitinated target within the pathological inclusions of amyotrophic lateral sclerosis