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These inflammatory factors significantly influence the biological behavior of MSCs in a manner that is both concentration- and cell source-dependent

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It usually begins between the ages of 50 and 70 and is slightly more common in men than women, with a male-to-female ratio of about 1.51 (Chi et al., 2013)

The combination of GLS inhibitors and ASNase has shown promising therapeutic potential against TP53-mutated CRPC tumors in experimental studies and may offer new approaches for the personalized treatment of these cancers