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10.1124/jpet.121.000537 39 Gomez-CadenaA.UruenC.PrietoK.Martinez-UsatorreA.DondaA.BarretoA.et al (2016)

Yerrington prior to treatment

Global, regional, and national burden of pulmonary arterial hypertension and related heart failure from 1990 to 2021, with predictions to 2050: insights from the global burden of disease study 2021

In studies related to non-small cell lung cancer, it has been observed that a reduction in amino acid metabolism, along with the inactivation of the mTOR signaling pathway, can lead to the exhaustion of CD8+ T cells, thereby diminishing the body's immune defense capabilities (91)