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An indirect evidence for an intrinsic cycle in Schwann cells has come from studies on bone marrow reorganisation revealing the nonmyelinating Schwann cells as regulators of the hematopoietic stem cell activity by keeping the hematopoietic stem cells in a hibernating state, from which they can switch to active proliferation, for example, after a haemorrhage (Yamazaki et al., 2011)

The pathological hallmark of AD is the deposition of amyloid plaques and neurofibrillary tangles in the gray matter due to aberrant processing of amyloid precursor protein (APP) leading to the aggregation of amyloid- (A) peptides and tau protein, respectively

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Thermo Fisher Scientific) for 6 h to stimulate antigen-specific T cells