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doi: 10.1016/j.jaccas.2019.12.013 575 BenjaminEJBlahaMJChiuveSECushmanMDasSRDeoRet al

Sirtuins are a class of nutrient-sensitive epigenetic information regulators, including in promoting mammalian health, modulating cellular senescence and lifespan, and Sirt1 is called the longevity gene