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Glutaredoxin catalysis requires two distinct glutathione interaction sites Nature Communications Cellgevity Alexora BioMedical Technologies Inc. Multiomics reveals glutathione metabolism as a driver of bimodality during stem cell aging: Cell Metabolism Cellgevity attenuates liver distruption, oxidative stress and inflammation in STZ diabetic male rats ScienceDirect

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Glutathione, a tripeptide containing cysteine, is a crucial antioxidant that guards against oxidative damage to cells [12]

The cysteine residues of p35 can also be S-nitrosylated, it was found that S-nitrosylation of p35 at Cys92 by NO signaling led to its ubiquitination and degradation, which resulted in the reduction of Cdk5 activity (Zhang et al., 2015)