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Binding of apoptosis-linked gene-2-interacting protein X to its N-terminal region promotes secretion, whereas keratin 20 binding at this region inhibits secretion and thereby prevents ferroptosis in kidney tubular cells [152]

Zhou JJ, Cho JS, Han H, Blitz IL, Wang W, Cho KWY

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183,184 IL-4 and IL-13 induce STAT6 in target cells with JAK involvement, and gene-targeted knockout mouse assays revealed STAT6 contributes to IgE synthesis, bronchial hyperresponsiveness and airway remodeling upon allergen sensitization