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mtDAMPs activate neutrophils and monocytes, which infiltrate tissues and release additional ROS and proteases, causing further mitochondrial damage and cell death

[470] demonstrated that sesamol treatment (100 mg/kg per day) for 6 weeks inhibited the DSS-induced bodyweight loss of mice, along with the DSS-induced histopathological changes and inflammatory responses by targeting the NF-B signaling pathway in mice colon

107 Moreover, hormone-sensitive tissues such as the breast, endometrium, and prostate also exhibit significant metabolic fluctuations in response to hormone levels

In conclusion, quercetin exhibits anti-inflammatory, antioxidant, and antimicrobial properties