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doi: 10.1080/0886022X.2020.1869043 54 WangWLongHHuangWZhangTXieLChenCet al

THEY ARE INTENDED FOR IN-VITRO AND PRE-CLINICAL RESEARCH PURPOSES ONLY

Tables 1 and 2 summarize passive membrane diffusion and active transport membrane permeability, respectively, for select small molecule NNMT inhibitors for which structure activity relationships had been previously developed.[17] 1-MNA, a product inhibitor of NNMT[12, 24, 25] exhibited no passive permeability (Table 1)