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Then, a Z-score was computed from the unadjusted p -value using a two-tailed test conversion [ Z = qnorm( p /2, lower.tail=FALSE) sign(logFC)]

(For additional details on our finalized policies related to the dual rate LTCH PPS payment structure required by statute, we refer readers to the FY 2016 IPPS/LTCH PPS final rule (80 FR 49601 through 49623).) Prior to the implementation of the dual payment rate system in FY 2016, all LTCH discharges were paid similarly to those now exempt from the site neutral payment rate

Thus, the influence of this system on the cellular drug sensitivity is not straightforward and depends on a number of parameters (as was described here for other mechanisms of drug resistance)

10.1016/j.jprot.2018.04.012 27 ClarkS