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Genes related to cytotoxicity were expressed on both Rej and nave subsets with no noticeable differences, while exhaustion markers were preferentially expressed on Rej liver(Fig B)

System xCT is instrumental in metabolic reprogramming, as it increases glucose consumption and lactate production, as well as glutamine dependency of cancer cells (68) ( Figure 3 )

The Cellular Redox System The cellular redox state refers to the balance between oxidation and reduction reactions (Calabrese et al., 2017

(2011) Thymosin 4 Improves Functional Neurological Outcome in Rat Embolic Stroke Model PMC2907184 Kleinman HK & Sosne G (2016) Thymosin 4 Promotes Dermal Healing Vitam Horm 102:251275