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The activation of intrinsic apoptotic pathway is characterized by MOMP and release of cytochrome c from mitochondria that consequently results in assembly of caspase-activation complexes and activation of caspase 9 51

The different ranges of FT4 are as follows: Q1: 8.339.72 pmol/L

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thus, it is recommended that the drug dosage should be modified based on the goal of glycemic control and the type of antidiabetes therapy when prescribing the KD to T2DM patients