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No completed, peer-reviewed human efficacy or long-term safety trial exists as of 2026

There are eight devices in the pipeline, one of which is a repurposed quinagolide-releasing vaginal ring, marketed for the treatment of pituitary gland tumours, which has showed positive results in reducing endometriosis lesions and improving pain symptoms in the human safety and efficacy phase

Environ Toxicol Chem 40:71577166 Mutlib AE (2008) Application of stable isotope-labeled compounds in metabolism and in metabolism-mediated toxicity studies

The immunohistochemical results indicate that acrylamide exposure induces significant neuroinflammation (indicated by GFAP staining) and neuronal apoptosis (indicated by caspase-3 staining)