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doi: 10.1017/S0007114513003425

Nitric oxide inhibits 5- reductase conversion of testosterone to DHT Dual wavelength LEDs reduce the conversion of testosterone to DHT by epithelial cells in vitro in vitro Step 1: Illuminate Cells Step 2: Add testosterone and/or finasteride Step 3: Competitive DHT ELISA Dual wavelength LED light induces NO and ROS production in epithelial cells in vitro in vitro Step 1: Add DAF-FM dictate (NO) or CellROX Deep Red Reagent (ROS) Step 2: Illuminate cells Step 3: Fluorescence microscopy Conclusions Dual wavelengths of 620 nm and 660 nm visible light maximally stimulate the production of reactive oxygen species and nitric oxide, decreasing the production of DHT in vitro

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Future research into these overlapping pathways may help in identifying novel therapeutic targets and strategies for managing NPS in AD more effectively