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1 Introduction The Mediterranean marine ecosystem has changed drastically over the past few decades due to biological invasions, which have affected both biodiversity and seafood consumption patterns (Azzurro et al., 2019

In the 1990s, Japanese researchers found that in children 5 years old or younger with low BH4 levels, supplemental tetrahydrobiopterin significantly improved autism symptoms in some.[ref] (To be clear, not all children with autism have low BH4 levels, nor will all respond to BH4)

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they are rapidly reinfected and must be retreated on an annual or semiannual basis