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The use of antioxidants such as glutathione during chemotherapy or radiation therapy is controversial and probably not recommended [6]

Enhances fatty acid oxidation by regulating beta-3 adrenergic receptor expression

Endoxifen, the most potent metabolite is produced via N - demethylation of tamoxifen to form N -desmethyltamoxifen (NDM) whereas CYP2D6 catalyzed 4-hydroxylation of NDM to form endoxifen