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In England and Wales, the Office for National Statistics reported that 2.4% of individuals aged 16 to 24 years used ecstasy in their survey Drug Misuse in England and Wales: year ending March 2023

However, there is still much room for improvement

In addition, we discuss the role of ATP-binding cassette transporters (ABC transporters), including ABCB1, ABCG2 and ABCC2, in mediating drug resistance and their importance for personalized treatment strategies