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They may call for: Complete fasting Water- or juice-only fasting Restrictive diets of only fruits and vegetables Use of herbs, teas, supplements, enemas or laxatives Such strict regimens like these may cause: Electrolyte imbalances Vitamin or mineral deficiencies, which is when your body does not receive or absorb enough of the essential micronutrients it needs to function properly Gastrointestinal issues like diarrhea Fatigue Breakdown of muscle These diets appear harmless since they use natural foods and products, but we do not have evidence that they are safe or that they work, says Lindsey Wohlford, a wellness dietitian at UT MD Anderson

doi: 10.3390/biom13030486

In this Review, we highlight the latest advances in our understanding of the mechanisms of action of metformin and discuss potential emerging novel therapeutic uses

S., Bashir, R., & Ali, S