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This mechanistic distinction means the compound could theoretically be combined with appetite-suppressing peptides for a protocol that simultaneously reduces energy intake (GLP-1) and restores adipocyte energy expenditure (NNMT inhibition) though this remains purely theoretical without published combination data

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It has excellent tumor-targeting and penetration properties, which can rapidly accumulate in the lesion and achieve a deep penetration effect

doi: 10.1523/jneurosci.23-08-03394.2003 20 Pakos-ZebruckaKKorygaIMnichKLjujicMSamaliAGormanAM