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doi: 10.1016/j.yexcr.2021.112800 64 ZhuZDuanPSongHZhouRChenT

10.1016/j.ejca.2005.09.011 29 DuL.WangH.HeL.ZhangJ.NiB.WangX.et al (2008)

Abstract Cancer treatment is hampered by resistance to conventional therapeutic strategies, including chemotherapy, immunotherapy, and targeted therapy

When these primary bile acids are secreted into the lumen of intestine, a portion of each is dehydroxylated by intestinal bacteria to produce the secondary bile acids, deoxycholic acid, and lithocholic acid.2, 5, 28 Prior to secretion, bile acids are conjugated with taurine and/or glycine to form tauro- and glycoconjugated bile salts (see Figure 61-3, C)