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A., Donachie, S

revealed significant bone loss of the femur in male but not female ARKO mice, as well as ARKO-induced increase in bone turnover in males only

The analysis of both the DBS and urine samples resulted in an atypical elimination behavior of meldonium: An initial phase with a rapid clearance of the active substance within the first 12-24 h was followed by a second substantially slower elimination phase, where concentrations of ca