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The therapeutic approaches currently applied in clinical practice not appear to be beneficial for these patients and, in some cases such as in transfusion of stored blood, may increase risk of mortality

Therefore, the findings of the present study that investigated the regulation pathways of CHAC1 probably contributed to elucidation of the induction mechanisms of ferroptosis and the future discovery of therapeutic targets of numerous ischemic injuries

The leaves are alternate, oblong, lanceolate, or narrowly ovate, with microwave-like serrations