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This variation affects heme production

Oral immunotherapy (OIT), a form of allergen-specific desensitization that increases the threshold for allergic reactions upon exposure, has been recommended by the European Academy of Allergy and Clinical Immunology (EAACI) for certain food allergies such as peanut, egg, and milk, primarily to reduce the risk of reactions from accidental exposure [13]

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ROS oxidize -SH groups of cysteine residues in protein kinases A, C, and D, receptor tyrosine kinase (RTK), and Ca/calmodulin independent protein kinase II, which in turn phosphorylate target proteins participating in various signaling mechanisms (Kruk et al