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(1) Statins diminish respiratory capacity at the level of complexes I (CI), II (CII), and III (CIII) of the respiratory chain, which in turn results in the increased generation of superoxide (O 2 ) generation

243 In another two studies, researchers found that myristoylation of the lysosomal adaptor mTOR activator 1 (LAMTOR1) by NMT1 at G2 promotes its palmitoylation and anchoring to the lysosome, which increases mTOR activity to inhibit autophagy and promote the progression of lung cancer, bladder cancer, colorectal cancer, and cervical carcinoma