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Progression of AD marked by the loss of neurons has been reported to be connected with reduced mitochondrial complex IV activity and increased ROS production (Misrani et al., 2021, Wang et al., 2020, Wong-Riley et al., 1997)

(Stimulated Egr-1 gene, NAB2, FAK-paxillin and JAK-2 pathways) BPC-157 Uses ORAL: 250-500 mcg by mouth daily in 1-2 divided doses SUBQ: 250-500mcg subcutaneously once-twice daily INTRAMUSCULAR: 250-500mcg as close to the site of injury as possible QD-BID SUBLINGUAL: 200-500 mcg between cheek and gum daily in 1-2 divided doses BPC-157 used to treat injuries We will use the ACL tendon in the knee as an example for this article

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Animal experiment BALB/c mice (45 weeks old, female) and BALB/c nude mice (45 weeks old, female) were purchased from SPF Biotechnology Co., Ltd