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It's not a DHT blocker, it doesn't have decades of clinical trial data, and it won't reverse a hairline that has been receding for twenty years

Melen et al

A possible role for selenoprotein glutathione peroxidase (Gpx1) and thioredoxin reductases (Trxr1) in thyroid cancer: Our experience in thyroid surgery

A pivotal study investigating liver fibrosis found that SIRT6 protects against fibrogenesis by deacetylation and suppression of SMAD3 in hepatic stellate cells, illustrating the complex pathways involved in chronic tissue stress