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2.Glutathion synthesis The first step of GSH synthesis is rate-limiting and catalyzed by glutamate-cysteine ligase (GCL) formerly referred to as -glutamylcysteine synthetase (GCS)

Previously, Zhu and team developed a dual-functional composite scaffold drug delivery system (CS-DDS) where drug-loaded MSNs were coated onto a -tricalcium phosphate (-TCP) scaffold with additional bioactive glass coating for osteoarticular tuberculosis therapy (Zhu et al., 2011)