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LiuMJBaoSGlvez-PeraltaMPyleCJRudawskyACPavloviczREet al

Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression

10.1017/S001216220600020X 11 BaellJ

Thus, our results suggest that the conformational flexibility of the EHL domain of OTU1 is crucial for K6-linked diubiquitin chain cleavage, and this conformational change in the EHL domain upon recognition of the ubiquitin moiety could be a unique characteristic of the Lot DUB family