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Whether that reshuffling translates into anything functional, into real changes in how a cell ages, behaves, or secretes molecules, is a separate question each study has to test on its own terms

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In peripheral blood -Syn stimulated cells, PD patients were detected with more IL-1 and IL-6 and less IL-10 than healthy controls, indicating an imbalance in the pro-inflammatory and anti-inflammatory cytokines in PD-associated neuroinflammation (Piancone et al., 2021)