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It is worth noting that the preclinical ASD models used in these studies show baseline dysregulation of the oxytocin system

Han Y, Chaouch S, Mhamdi A, Queval G, Zechmann B, Noctor G (2013) Functional analysis of Arabidopsis mutants points to novel roles for glutathione in coupling H 2 O 2 to activation of salicylic acid accumulation and signaling

The overexpressed GSH in cancer cells would degrade the framework of Fe(II)-BNCP, and trigger rapid NO liberation in situ , thereby leading to synergistic NO-CDT effect for the retardation of tumor growth