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(IV) Although many researchers have devoted themselves to uncovering the precise mechanisms of ferroptosis and have made some achievements, the existing studies mostly focused on the upstream pathways of lipid peroxidation, leaving largely unexplored the downstream molecular pathways or key molecular junctions after the initiation of ferroptosis

Pharmacotherapy 37(5):55578 Adamczyk-Sowa M, Pierzchala K, Sowa P, Mucha S, Sadowska-Bartosz I, Adamczyk J, Hartel M (2014) Melatonin acts as antioxidant and improves sleep in MS patients

Solvent selection and working-solution preparation must follow institutional laboratory SOPs

235,236,237,238 However, the disadvantages such as poor solubility and negative material-biological interface interactions limit their further applications