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SoppertJBrandtEFHeussenNMBarzakovaEBlankLMKuepferLet al

doi: 10.1073/pnas.1511389112 199 IsbergR

This design choice was deliberate

Second, the two effects that actually warrant hard limits rising IGF-1 and impaired glucose tolerance are the ones tied to Tesamorelins real prescribing label, which is why they are framed as monitored parameters rather than nuisances