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392 Immune checkpoint inhibitors (ICIs) therapy has demonstrated remarkable effectiveness in TNBC, prompting numerous centers to investigate its perioperative value in HR+/HER2 breast cancer

Feature importance was computed using rangers permutation variable importance approach 108 , and then starting with the least important, each input feature was set to the mean value from the training dataset for that feature and the AUC score or Spearman rho coefficient was computed for the testing set and the ZOE PREDICT1 dataset

Supplementing with ALCAR helps regenerate components required for the Krebs cycle, resulting in more efficient energy production

doi: 10.1016/j.idairyj.2023.105608 175