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doi: 10.1016/j.brainres.2010.11.013 49 LiRWuYZouSWangXLiYXuKet al

The direct evidence of oxidative stress in cancer cells is demonstrated by the significantly elevated levels of ROS in cancer cells compared to normal cells [75, 76], while the indirect proof is obtained through the markedly increased levels of lipid peroxidation products [77, 78]