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It is important that exogenous GSH not only significantly increased the content of total glutathione (by 40%) but also increased the endogenous content of its reduced form in cardiac tissue, thus contributing to maintenance of the redox potential of mitochondria and cardiac cells in general

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Conversely, too much iodine, often from kelp or seaweed supplements, can actually shut the thyroid down or trigger an autoimmune response in sensitive individuals

Thus, heterologous OsDHAR expression in the TA responded to oxidative stress by increasing the number of redox active sites, such as GSH binding sites, and GSTs with similar functionally conserved residues under these conditions (Figures 1, 5)