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A version of this article first appeared in CNBC's Healthy Returns newsletter, which brings the latest health-care news straight to your inbox

105 Activation of the RhoA/ROCK pathway impairs NO bioavailability through inhibition of eNOS mRNA stability, eNOS posphorylation at Ser 1177 and the Akt/PI3K pathway and enhancement of eNOS phosphorylation at Thr495

The resulting HSA-Mn 3 O 4 and HSA-TI are then cross-linked via ROS-cleavable thioketal linkers and covalently immobilized onto platelet, forming the platelet-nano assemblies 55