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doi: 10.1016/j.semcancer.2009.10.005

The strongest human evidence is topical, including the Leyden 2002 photoaging trial and a 2023 IRB-approved 21-woman topical NEEL gel study reporting an average 28% increase in skin collagen density at 3 months

Vitamin B12 is a key contributor to the bodys formation of cells, particularly in helping to create healthy red blood cells, and is now considered an essential piece of someones overall wellness regime

Dysfunction of T and B cells drives anti-nuclear antibody production through the release of oxidized immunogenic nuclear materials from necrotic rather than apoptotic cells (Perl 2013)