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PMID: 24711953 National Institutes of Health

Moreover, intense exercise, as experienced by athletes and those committed to their physical craft, takes a biochemical toll as well

CNS 2024-154488)

To explore this idea, we bred the MMTV-PyMT transgenic mouse strain (which spontaneously develops breast tumours) 26 with an uninduced Gclc f/f Rosa26 creERT2 mouse 27 in which the rate-limiting step in GSH synthesis, the glutamatecysteine ligase catalytic subunit (GCLC), can be knocked out throughout the body after induction with tamoxifen